- What is a Dry Syrup Powder Filling Machine?
- How does a Dry Syrup Powder Filling Machine work?
- When to choose a Dry Syrup Powder Filling Machine
- Where is a Dry Syrup Powder Filling Machine used?
- Why choose our Dry Syrup Powder Filling Machine
- Technical specifications
- Frequently Asked Questions
What is a Dry Syrup Powder Filling Machine?
A Dry Syrup Powder Filling Machine is a piece of pharmaceutical packaging equipment that fills antibiotic dry syrup powders (such as amoxicillin, azithromycin, and cefixime) into amber glass bottles, then caps them with ROPP aluminium caps. The machine is typically part of an integrated dry syrup line that includes bottle unscrambling, powder filling, cap feeding, and capping.
Unlike a generic auger powder filling machine, a dry syrup filler is purpose-built for the requirements of antibiotic dry syrups: amber glass bottles (to protect against UV), ROPP aluminium caps (to provide tamper evidence and a moisture barrier), and recipe management for the active ingredient and flavour system.
The purpose of a dry syrup powder filling machine is clear: deliver the exact dose of dry syrup into an amber glass bottle, sealed with a tamper-evident ROPP cap, batch after batch, at the highest GMP standard.
How does a Dry Syrup Powder Filling Machine work?
The dry syrup filling cycle is a synchronised sequence of bottle indexing, auger dosing, and ROPP capping steps. Here is the step-by-step process:
- Bottle in-feed: Amber glass bottles are unscrambled (manually for small lines, automatically for high-speed lines) and loaded on the infeed conveyor.
- Bottle orientation and indexing: A star wheel orients and indexes the bottle under the auger nozzle.
- Nitrogen flush (optional but standard): A nozzle purges the bottle headspace with food-grade nitrogen to displace oxygen and protect oxidation-sensitive actives such as certain beta-lactams.
- Auger dosing: A servo-driven auger dispenses a precise dose (typically 10 g to 100 g) of dry syrup powder. Dose accuracy is ±0.5% to ±1% with the right auger pitch and powder flow.
- Cap feeding: ROPP aluminium caps are oriented in a vibratory bowl feeder and delivered to the capper.
- ROPP capping: A servo-driven capping head with torque control tightens the ROPP cap to a pre-set value (typically 10–16 inch-lb).
- Output: Capped bottles exit on the conveyor to the labelling machine, inspection booth, or cartoning line.
The complete process is controlled by a PLC with an HMI touchscreen. Operators store bottle recipes (bottle size, dose, auger speed, capping torque, nitrogen flush time), and recall them with a single tap on the HMI.
When to choose a Dry Syrup Powder Filling Machine
Choosing the right powder filling technology saves both capex and validation effort. Use this honest decision guide:
Choose Dry Syrup Filler
When you fill antibiotic dry syrups in amber glass bottles with ROPP caps and need nitrogen-flushed headspace.
Choose Auger Powder Filler
When you fill free-flowing powders (protein, ORS, churna) in HDPE jars or pouches and do not need ROPP capping.
Choose Single Head
When your batch is under 15,000 bottles per shift, you run multiple SKUs, or you are a contract manufacturer with frequent changeovers.
Choose Double Head
When your batch exceeds 25,000 bottles per shift, you run a few high-volume SKUs, or you want headroom for future demand growth.
Where is a Dry Syrup Powder Filling Machine used?
A dry syrup powder filling machine is one of the most common pieces of pharmaceutical packaging equipment in India. The pharmaceutical version is the strictest in build and documentation, but the same core machine is used in:
- Antibiotic dry syrups — amoxicillin, amoxicillin-clavulanate, azithromycin, cefixime, cephalexin, cefpodoxime in amber glass bottles.
- Probiotic dry syrups — lactobacillus and saccharomyces formulations for paediatric use.
- Rehydration salts (ORS) — powder form in 30 ml to 200 ml amber glass or HDPE bottles.
- Antifungal dry syrups — fluconazole, itraconazole powder formulations.
- Antihistamine dry syrups — cetirizine, levocetirizine powder formulations.
Our dry syrup powder filling machines are installed across India and in 25+ export markets. Every machine is built at our Ahmedabad facility and dispatched with full IQ/OQ documentation on request.
Why choose our Dry Syrup Powder Filling Machine
We are not the largest dry syrup equipment brand in India, and we will not pretend to be. What we will say is that every dry syrup powder filling machine we ship is engineered honestly — built for your product, not for a catalogue.
GMP-Compliant Build
SS316 contact parts, sanitary tri-clamp fittings, Ra ≤ 0.8 µm finish on product zones.
Servo Auger Dosing
±0.5% to ±1% dose accuracy with recipe storage — repeatable across batches and audits.
ROPP Capping
Servo-driven torque control rejects over- and under-tightened caps automatically.
Nitrogen Flushing
In-line N2 flush before fill to protect oxidation-sensitive actives.
HEPA Dust Extraction
Localised exhaust with HEPA filtration keeps the fill zone clean and operator-safe.
Hopper Agitator
Variable-speed agitator breaks powder bridges and keeps the feed consistent.
Quick Changeover
Tool-free change parts, typically under 15 minutes per SKU.
PLC + HMI Control
Delta / Siemens platform with audit trail and 21 CFR Part 11 ready (optional).
IQ / OQ / PQ Documents
Full validation support for WHO-GMP, cGMP, and USFDA plants.
1-Year Warranty
Comprehensive warranty with on-call service across India.
Dry Syrup Powder Filling Machine — Technical Specifications
The table below lists the standard range. Custom configurations are available for larger doses, larger bottles, or specific validation requirements. Contact our sales team for a tailored datasheet.
| Parameter | Standard Range |
|---|---|
| Product Name | Dry Syrup Powder Filling Machine |
| Machine Type | Single-head or double-head auger filling machine with ROPP capping system |
| Output Speed | 30–80 bottles per minute |
| Filling Heads | 1 or 2 filling heads in single-head or dual-head configuration |
| Capping Heads | 1 or 2 ROPP capping heads |
| Dose Range | 5 g–200 g with interchangeable augers |
| Dose Accuracy | ±0.5% to ±1% of the set dose |
| Auger Drive | Servo motor with closed-loop feedback control |
| Hopper Capacity | 25–100 litre SS316 hopper with powder-level sensor |
| Hopper Agitator | Variable-speed powder agitator |
| Bottle Type | Amber glass bottles; also suitable for clear glass and HDPE bottles |
| Bottle Diameter | 30 mm–60 mm |
| Bottle Height | 60 mm–180 mm |
| Cap Type | ROPP aluminium screw cap |
| Capping Torque | Adjustable from 10–16 in-lb |
| Nitrogen Flush | Programmable in-line nitrogen-flushing system |
| Dust Extraction | HEPA-filtered dust-collection system |
| Reject System | Optional automatic detection and rejection for missing caps and low-fill bottles |
| Contact Parts Material | SS316 stainless steel with a sanitary surface finish |
| Non-Contact Parts | SS304 stainless steel with suitable engineering plastics |
| Control System | PLC with colour HMI from Delta, Siemens or Mitsubishi |
| Power Supply | 415 V AC, 3-phase, 50 Hz |
| Air Supply | 6 bar oil-free compressed air |
| Documentation | IQ, OQ and PQ support with CE and cGMP documentation; optional 21 CFR Part 11 support |
| Warranty | 12 months from the date of dispatch |
Frequently Asked Questions — Dry Syrup Powder Filling Machine
A Dry Syrup Powder Filling Machine is a piece of pharmaceutical packaging equipment that fills antibiotic dry syrup powders (such as amoxicillin, azithromycin, and cefixime) into amber glass bottles, then caps them with ROPP aluminium caps. The machine is part of an integrated dry syrup line that includes bottle unscrambling, powder filling, cap feeding, and capping.
A Dry Syrup Powder Filling Machine works by indexing amber glass bottles under an auger dosing station, dispensing a precise dose (typically 10 g to 100 g) of dry syrup powder, and then feeding a ROPP cap and tightening it with torque control. Optional nitrogen flushing is done before filling to protect the active ingredient.
An automatic Dry Syrup Powder Filling Machine typically runs at 30 to 80 bottles per minute. The speed depends on dose size, auger pitch, and whether the line is integrated with bottle unscrambling, capping, and labelling.
The Dry Syrup Powder Filling Machine handles amber glass bottles from 30 ml to 200 ml in standard configuration. Bottle diameter is typically 30 mm to 60 mm. Common sizes include 30 ml, 60 ml, 100 ml, and 200 ml amber glass bottles used for paediatric dry syrups.
Yes. Pharma-grade Dry Syrup Powder Filling Machines are built with SS316 contact parts, sanitary tri-clamp fittings, contained auger enclosures with HEPA-filtered dust extraction, and optional nitrogen flushing. They support IQ/OQ documentation for WHO-GMP, cGMP, and USFDA plants.
A Dry Syrup Powder Filling Machine in India typically ranges from ₹ 8 lakh for a semi-automatic model to ₹ 35 lakh for a fully integrated GMP line with bottle unscrambler, auger filler, ROPP capper, nitrogen flush, and IQ/OQ documents. Contact us with your bottle size, dose, and target output for a tailored quote.
An Auger Powder Filling Machine is a general-purpose powder filler for any free-flowing or semi-free-flowing powder. A Dry Syrup Filling Machine is purpose-built for antibiotic dry syrups in amber glass bottles, with integrated ROPP capping, nitrogen flushing, and recipe management specific to dry syrups.
A Dry Syrup Powder Filling Machine is used in pharmaceutical plants that manufacture paediatric dry syrup antibiotics (amoxicillin, azithromycin, cefixime, cephalexin), probiotic dry syrups, and rehydration salts. It is also used in contract manufacturing and 3rd-party pharma packaging units.
Yes. The Dry Syrup Powder Filling Machine supports in-line nitrogen flushing before filling. The nozzle purges the bottle headspace with food-grade nitrogen to displace oxygen and protect oxidation-sensitive actives such as certain beta-lactams.
Our Dry Syrup Powder Filling Machine ships with a calibration certificate, SS316 material traceability, and a complete IQ/OQ protocol template. WHO-GMP, cGMP, and USFDA documentation packs are available on request, including DQ, IQ, OQ, PQ and 21 CFR Part 11 ready controls.
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